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Article

Coexpression of wild-type and mutant prion proteins alters their cellular localization and partitioning into detergent-resistant membranes.

Traffic (Copenhagen, Denmark) - 1 Jul 2008

Schiff Edwin, Campana Vincenza, Tivodar Simona, Lebreton Stéphanie, Gousset Karine, Zurzolo Chiara

Abstract excerpt

Transmissible spongiform encephalopathies (TSEs) are a group of diseases of infectious, sporadic and genetic origin, found in higher organisms and caused by the pathological form of the prion protein. The inheritable subgroup of TSEs is linked to insertional or point mutations in the prion gene prnp, which favour its misfolding and are passed on to offspring in an autosomal-dominant fashion. The large majority of...

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Identifiers

PMID: 18410485
DOI: 10.1111/j.1600-0854.2008.00746.x

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GSS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Coexpression of wild-type and mutant prion proteins alters their cellular localization and partitioning into detergent-resistant membranes.PMID 18410485Read ↗

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