Article
Molecular characterization of erythrocyte glycophorin C variants.
Blood - 1 Feb 1991
Chang S, Reid M E, Conboy J, Kan Y W, Mohandas N
Abstract excerpt
Human erythrocyte glycophorin C plays a functionally important role in maintaining erythrocyte shape and regulating membrane mechanical stability. Immunochemical and serologic studies have identified a number of glycophorin C variants that include the Yus, Gerbich, and Webb phenotypes. We report here the molecular characterization of these variants. Amplification of glycophorin C mRNA from the Yus phenotype,...
Topics
- Amino Acid Sequence
- Base Sequence
- Chromosome Deletion
- Erythrocyte Membrane
- Gene Amplification
- Genetic Variation
- Glycophorins
- Humans
- Immunohistochemistry
- Molecular Sequence Data
- Molecular Structure
