Article
Lack of influence of COMT Val158Met genotype on cognition in first-episode non-affective psychosis.
Schizophrenia research - 1 Jul 2008
Mata Ignacio, Perez-Iglesias Rocio, Pelayo-Teran Jose Maria, Rodríguez-Sanchez Jose Manuel, Gonzalez-Blanch Cesar, Carrasco-Marin Eugenio, Vazquez-Barquero Jose Luis, Crespo-Facorro Benedicto
Abstract excerpt
COMT gene is a logical candidate gene for schizophrenia. Moreover, variations in the COMT Val158Met functional polymorphism have been associated with prefrontal cognitive abnormalities among patients with schizophrenia, healthy relatives and controls. In this study, using an epidemiologically-based sample of 130 patients experiencing a first-episode of a non-affective psychosis, we examined whether COMT Val158Met...
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