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Article

Mycobacterium tuberculosis prevents inflammasome activation.

Cell host & microbe - 17 Apr 2008

Master Sharon S, Rampini Silvana K, Davis Alexander S, Keller Christine, Ehlers Stefan, Springer Burkhard, Timmins Graham S, Sander Peter, Deretic Vojo

Abstract excerpt

Mycobacterium tuberculosis (Mtb) parasitizes host macrophages and subverts host innate and adaptive immunity. Several cytokines elicited by Mtb are mediators of mycobacterial clearance or are involved in tuberculosis pathology. Surprisingly, interleukin-1beta (IL-1beta), a major proinflammatory cytokine, has not been implicated in host-Mtb interactions. IL-1beta is activated by processing upon assembly of the...

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Source

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Identifiers

PMID: 18407066
DOI: 10.1016/j.chom.2008.03.003
PMCID: PMC3657562

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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