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Article

Interaction of Mycobacteria With Host Cell Inflammasomes

14 Feb 2022

Abstract excerpt

The inflammasome complex is important for host defense against intracellular bacterial infections. Mycobacterium tuberculosis (Mtb) is a facultative intracellular bacterium which is able to survive in infected macrophages. Here we discuss how the host cell inflammasomes sense Mtb and other related mycobacterial species. Furthermore, we describe the molecular mechanisms of NLRP3 inflammasome sensing of Mtb which...

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Identifiers

PMID: 35237260
DOI: 10.3389/fimmu.2022.791136

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