Article
Wollknauel is required for embryo patterning and encodes the Drosophila ALG5 UDP-glucose:dolichyl-phosphate glucosyltransferase.
Development (Cambridge, England) - 1 May 2008
Haecker Achim, Bergman Mattias, Neupert Christine, Moussian Bernard, Luschnig Stefan, Aebi Markus, Mannervik Mattias
Abstract excerpt
N-linked glycosylation is a prevalent protein modification in eukaryotic cells. Although glycosylation plays an important role in cell signaling during development, a role for N-linked glycosylation in embryonic patterning has not previously been described. In a screen for maternal factors involved in embryo patterning, we isolated mutations in Drosophila ALG5, a UDP-glucose:dolichyl-phosphate...
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