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Analysis of infectious virus clones from two HIV-1 superinfection cases suggests that the primary strains have lower fitness

20 Jul 2010

Abstract excerpt

BACKGROUND: Two HIV-1 positive patients, L and P, participating in the Amsterdam Cohort studies acquired an HIV-1 superinfection within half a year from their primary HIV-1 infection (Jurriaans et al., JAIDS 2008, 47:69-73). The aim of this study was to compare the replicative fitness of the primary and superinfecting HIV-1 strains of both patients. The use of isolate-specific primer sets indicated that the...

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PMID: 20646276
DOI: 10.1186/1742-4690-7-60

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