Article
Organismal, genetic, and transcriptional variation in the deeply sequenced gut microbiomes of identical twins.
Proceedings of the National Academy of Sciences of the United States of America - 20 Apr 2010
Turnbaugh Peter J, Quince Christopher, Faith Jeremiah J, McHardy Alice C, Yatsunenko Tanya, Niazi Faheem, Affourtit Jason, Egholm Michael, Henrissat Bernard, Knight Rob, Gordon Jeffrey I
Abstract excerpt
We deeply sampled the organismal, genetic, and transcriptional diversity in fecal samples collected from a monozygotic (MZ) twin pair and compared the results to 1,095 communities from the gut and other body habitats of related and unrelated individuals. Using a new scheme for noise reduction in pyrosequencing data, we estimated the total diversity of species-level bacterial phylotypes in the 1.2-1.5 million...
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