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Article

Lack of influence of the apolipoprotein E genotype on the outcome of selegiline treatment in Alzheimer's disease.

Dementia and geriatric cognitive disorders - 1 Jan 2003

Kálmán János, Juhász Anna, Rimanóczy Agnes, Palotás András, Palotás Miklós, Szabó Zoltán, Boda Krisztina, Márki-Zay János, Janka Zoltán

Abstract excerpt

The objective of our study was to investigate whether an interaction exists between apolipoprotein E (APOE) genotype and the response of patients with Alzheimer's disease (AD) to selegiline treatment, and whether APOE genotype independently affects the rate of AD progression. A 48-week multicenter double-blind trial was undertaken on 43 patients with mild to moderate AD. Primary efficacy measures were the AD...

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Source

Identifiers

PMID: 12714797
DOI: 10.1159/000069990

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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