Article
Tlx1 and Tlx3 coordinate specification of dorsal horn pain-modulatory peptidergic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 9 Apr 2008
Xu Yi, Lopes Claudia, Qian Ying, Liu Ying, Cheng Leping, Goulding Martyn, Turner Eric E, Lima Deolinda, Ma Qiufu
Abstract excerpt
The dorsal spinal cord synthesizes a variety of neuropeptides that modulate the transmission of nociceptive sensory information. Here, we used genetic fate mapping to show that Tlx3(+) spinal cord neurons and their derivatives represent a heterogeneous population of neurons, marked by partially overlapping expression of a set of neuropeptide genes, including those encoding the anti-opioid peptide cholecystokinin,...
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