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Article

Strain-associated variations in abnormal PrP trafficking of sheep scrapie.

Brain pathology (Zurich, Switzerland) - 1 Jan 2009

Jeffrey Martin, McGovern Gillian, Goodsir Caroline M, Síso Silvia, González Lorenzo

Abstract excerpt

Prion diseases are associated with the accumulation of an abnormal form of the host-coded prion protein (PrP). It is postulated that different tertiary or quaternary structures of infectious PrP provide the information necessary to code for strain properties. We show here that different light microscopic types of abnormal PrP (PrP(d)) accumulation found in each of 10 sheep scrapie cases correspond...

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Identifiers

PMID: 18400047
DOI: 10.1111/j.1750-3639.2008.00150.x
PMCID: PMC2659386

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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