Article
Fibroblast migration is mediated by CD44-dependent TGF beta activation.
Journal of cell science - 1 May 2008
Acharya Pinak S, Majumdar Sonali, Jacob Michele, Hayden James, Mrass Paul, Weninger Wolfgang, Assoian Richard K, Puré Ellen
Abstract excerpt
CD44 contributes to inflammation and fibrosis in response to injury. As fibroblast recruitment is critical to wound healing, we compared cytoskeletal architecture and migration of wild-type (CD44WT) and CD44-deficient (CD44KO) fibroblasts. CD44KO fibroblasts exhibited fewer stress fibers and foca...
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