Article
Joining the fingers: a HOXD13 Story.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jan 2014
Brison Nathalie, Debeer Philippe, Tylzanowski Przemko
Abstract excerpt
Synpolydactyly (SPD, OMIM 186000) is a rare congenital limb disorder characterized by syndactyly between the third and fourth fingers and between the fourth and fifth toes, with partial or complete digit duplication in the syndactylous web. The majority of these anomalies co-segregate with mutations in the HOXD13 gene,a homeobox transcription factor crucial for distal limb development. Different classes of HOXD13...
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