Article
Impact of germinal center and non-germinal center phenotypes on overall and failure-free survival after high-dose chemotherapy and auto-SCT in primary diffuse large B-cell lymphoma.
Bone marrow transplantation - 1 Jul 2008
Nyman H, Jantunen E, Juvonen E, Elonen E, Böhm J, Kosma V-M, Enblad G, Karjalainen-Lindsberg M-L, Leppä S
Abstract excerpt
Non-germinal center (non-GC) phenotype is an adverse prognostic factor in chemotherapy (CT)-treated diffuse large B-cell lymphoma (DLBCL) patients. To determine how high-dose therapy (HDT) supported with auto-SCT as first line therapy influences GC-associated outcome in young high-risk DLBCL patients GC and non-GC phenotypes were determined immunohistochemically from 63 patients. Of these, 29 primary high-risk...
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