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Article

TP53 mutations predict for poor survival in de novo diffuse large B-cell lymphoma of germinal center subtype.

Leukemia research - 1 Jan 2009

Zainuddin Norafiza, Berglund Mattias, Wanders Alkwin, Ren Zhi-Ping, Amini Rose-Marie, Lindell Monica, Kanduri Meena, Roos Göran, Rosenquist Richard, Enblad Gunilla

Abstract excerpt

Presence of TP53 mutations has been associated with poor prognosis in diffuse large B-cell lymphoma (DLBCL), although this has remained controversial. The TP53 codon 72 polymorphism has shown negative impact on cancer survival, but this has not been analyzed in DLBCL. Furthermore, the MDM2 SNP309...

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Share to MDM2 gene
Share to Lymphoma, B-Cell
Share to Lymphoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Tumor Suppressor Protein p53

Share to Viral-associated cancers and disorders

Source

Identifiers

PMID: 18706692
DOI: 10.1016/j.leukres.2008.06.022

Genes

MDM2
LSS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18706692-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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