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Article

Germinal center phenotype and bcl-2 expression combined with the International Prognostic Index improves patient risk stratification in diffuse large B-cell lymphoma.

Blood - 15 Feb 2002

Barrans Sharon L, Carter Ian, Owen Roger G, Davies Faith E, Patmore Russell D, Haynes Andrew P, Morgan Gareth J, Jack Andrew S

Abstract excerpt

The International Prognostic Index (IPI) identifies poor- and good-risk patients with diffuse large B cell lymphoma (DLBCL); however, the majority of patients have an intermediate IPI, with an uncertain prognosis. To determine whether cellular factors can be combined with the IPI to more accurately predict outcome, we have analyzed 177 presentation nodal DLBCLs for the expression of bcl-2 and a germinal center...

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Share to Germinal Center
Share to Lymphoma, B-Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphoma, Large B-Cell, Diffuse

Share to Polymorphism, Single-Stranded Conformational

Share to Proto-Oncogene Proteins c-bcl-2

Share to Risk Assessment

Share to Survival Analysis

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 11830458
DOI: 10.1182/blood.v99.4.1136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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