Article
Prognostic impact of activated B-cell focused classification in diffuse large B-cell lymphoma patients treated with R-CHOP.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2009
Nyman Heidi, Jerkeman Mats, Karjalainen-Lindsberg Marja-Liisa, Banham Alison H, Leppä Sirpa
Abstract excerpt
Gene expression profiling studies initially enabled diffuse large B-cell lymphoma to be divided into germinal center and activated B-cell-like subtypes, which define high- and low-risk patient groups when treated with chemotherapy. Attempts to reproduce the prognostic classification immunohistochemically have, however, provided inconsistent results. The aim of this study was to determine whether modified...
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