Article
A haplotype of the human CXCR1 gene protective against rapid disease progression in HIV-1+ patients.
Proceedings of the National Academy of Sciences of the United States of America - 27 Feb 2007
Vasilescu A, Terashima Y, Enomoto M, Heath S, Poonpiriya V, Gatanaga H, Do H, Diop G, Hirtzig T, Auewarakul P, Lauhakirti D, Sura T, Charneau P, Marullo S, Therwath A, Oka S, Kanegasaki S, Lathrop M, Matsushima K, Zagury J-F, Matsuda F
Abstract excerpt
Chemokines and their receptors are key factors in the onset and progression of AIDS. Among them, accumulating evidence strongly indicates the involvement of IL-8 and its receptors, CXCR1 and CXCR2, in AIDS-related conditions. Through extensive investigation of genetic variations of the human CXCR...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.