Article
Functional characterization of three G protein-coupled receptors for pigment dispersing factors in Caenorhabditis elegans.
The Journal of biological chemistry - 30 May 2008
Janssen Tom, Husson Steven J, Lindemans Marleen, Mertens Inge, Rademakers Suzanne, Ver Donck Kris, Geysen Johan, Jansen Gert, Schoofs Liliane
Abstract excerpt
Here, we report the identification, cloning, and functional characterization of three Caenorhabditis elegans G protein-coupled pigment dispersing factor (PDF) receptors, which we designated as Ce_PDFR-1a, -b, and -c. They represent three splice isoforms of the same gene (C13B9.4), which share a high degree of similarity with the Drosophila PDF receptor and are distantly related to the mammalian vasoactive...
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