Article
Drosophila GPCR Han is a receptor for the circadian clock neuropeptide PDF.
Neuron - 20 Oct 2005
Hyun Seogang, Lee Youngseok, Hong Sung-Tae, Bang Sunhoe, Paik Donggi, Kang Jongkyun, Shin Jinwhan, Lee Jaejung, Jeon Keunhye, Hwang Seungyoon, Bae Eunkyung, Kim Jaeseob
Abstract excerpt
The pigment-dispersing factor (PDF) is a neuropeptide controlling circadian behavioral rhythms in Drosophila, but its receptor is not yet known. From a large-scale temperature preference behavior screen in Drosophila, we isolated a P insertion mutant that preferred different temperatures during the day and night. This mutation, which we named han, reduced the transcript level of CG13758. We found that Han was...
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