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Article

Estrogen receptor alpha polymorphism is associated with pelvic organ prolapse risk.

International urogynecology journal and pelvic floor dysfunction - 1 Aug 2008

Chen Huey-Yi, Chung Ya-Wen, Lin Wei-Yong, Chen Wei-Chi, Tsai Fuu-Jen, Tsai Chang-Hai

Abstract excerpt

Estrogen and estrogen receptors are known to play important roles in the pathophysiology of pelvic organ prolapse (POP). We investigated whether estrogen receptor alpha (ERalpha) gene polymorphisms were associated with POP risk by conducting a case-control association study in 88 women with POP and 153 women without POP. Genotypes of the ERalpha (ESR1) gene polymorphisms (rs17847075, rs2207647, rs2234693,...

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Source

Identifiers

PMID: 18385916
DOI: 10.1007/s00192-008-0603-1

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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