Article
Progesterone receptor polymorphism is associated with pelvic organ prolapse risk.
Acta obstetricia et gynecologica Scandinavica - 1 Jan 2009
Chen Huey-Yi, Chung Ya-Wen, Lin Wei-Yong, Chen Wen-Chi, Tsai Fuu-Jen, Tsai Chang-Hai
Abstract excerpt
Progesterone and progesterone receptors (PGR) are known to play important roles in the pathophysiology of pelvic organ prolapse (POP). We investigated whether the PGR gene polymorphisms were associated with POP by conducting a case-control association study in 87 women with POP and 150 women without POP. Genotypes of the PGR gene polymorphisms (rs500760 and rs484389) were determined by polymerase chain reaction,...
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