Article
Promiscuous recombination of LoxP alleles during gametogenesis in cornea Cre driver mice.
Molecular vision - 20 Mar 2008
Weng Daniel Y, Zhang Yujin, Hayashi Yasuhito, Kuan Chia-Yi, Liu Chia-Yang, Babcock George, Weng Wei-Lan, Schwemberger Sandy, Kao Winston W-Y
Abstract excerpt
PURPOSE: To examine whether promiscuous Cre/LoxP recombination happens during gametogenesis in double transgenic mice carrying LoxP modified alleles and Cre transgene driven by tissue-specific promoter outside the gonads of adult mice. METHODS: Cre driver mice were crossbred with reporter mouse lines (e.g., ZEG and Rosa26R) to obtain Cre/ZEG and Cre/Rosa26R double transgenic mice. The frequency of promiscuous...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.