Article
Monoallelic expression of Krt12 gene during corneal-type epithelium differentiation of limbal stem cells.
Investigative ophthalmology & visual science - 1 Sept 2010
Hayashi Yasuhito, Call Mindy K, Liu Chia-Yang, Hayashi Miyuki, Babcock George, Ohashi Yuichi, Kao Winston W-Y
Abstract excerpt
PURPOSE: The purpose of this study was to characterize a Krt12-Cre knock-in mouse line for corneal epithelium-specific gene ablation and to analyze the allelic selection of the keratin 12 (Krt12) gene during corneal type-epithelium differentiation. METHODS: Knock-in mice were generated by gene targeting. The authors examined the expression patterns of several reporter genes in the corneas of bitransgenic...
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