Article
Minimal components of the RNA polymerase II transcription apparatus determine the consensus TATA box.
Nucleic acids research - 1 May 2008
Bjornsdottir Gudrun, Myers Lawrence C
Abstract excerpt
In Saccharomyces cerevisiae, multiple approaches have arrived at a consensus TATA box sequence of TATA(T/A)A(A/T)(A/G). TATA-binding protein (TBP) affinity alone does not determine TATA box function. To discover how a minimal set of factors required for basal and activated transcription contributed to the sequence requirements for a functional TATA box, we performed transcription reactions using highly purified...
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