Article
Tumor necrosis factor (TNF)-α -308G/A (rs1800629) polymorphism distribution in North India and its association with pemphigus: Case-control study and meta-analysis.
Autoimmunity - 1 Jan 2016
Dar Sajad Ahmad, Akhter Naseem, Haque Shafiul, Singh Taru, Mandal Raju Kumar, Ramachandran Vishnampettai Ganapathysubramanian, Bhattacharya Sambit Nath, Banerjee Basu Dev, Das Shukla
Abstract excerpt
Pemphigus is an autoimmune blistering disorder of skin and/or mucosal surfaces characterized by intraepithelial lesions and immunoglobulin-G autoantibodies against desmogleins (proteins critical in cell-to-cell adhesion). Genetic, immunological, hormonal, and environmental factors are known to contribute to its etiology. Tumor necrosis factor-alpha (TNF-α) which plays a key role in pathogenesis of many infectious...
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