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Article

Twin study refining psychotic symptom dimensions as phenotypes for genetic research.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Oct 2008

Cardno Alastair G, Rijsdijk Frühling V, Murray Robin M, McGuffin Peter

Abstract excerpt

We investigated which psychotic symptom dimensions are likely to be most useful as phenotypes for genetic linkage and association studies. Two hundred twenty-four probandwise twin pairs (106 monozygotic,118 same-sex dizygotic), where probands had psychosis, were ascertained from the Maudsley Twin Register in London. Dimensions were defined as ordinal symptom scores using the OPCRIT checklist, based on previous...

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PMID: 18384051
DOI: 10.1002/ajmg.b.30756

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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