Article
Inference from genome-wide association studies using a novel Markov model.
Genetic epidemiology - 1 Sept 2008
Hosking Fay J, Sterne Jonathan A C, Smith George Davey, Green Peter J
Abstract excerpt
In this paper we propose a Bayesian modeling approach to the analysis of genome-wide association studies based on single nucleotide polymorphism (SNP) data. Our latent seed model combines various aspects of k-means clustering, hidden Markov models (HMMs) and logistic regression into a fully Bayesian model. It is fitted using the Markov chain Monte Carlo stochastic simulation method, with Metropolis-Hastings...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
