Article
Investigative role of pre-microRNAs in bladder cancer patients: a case-control study in North India.
DNA and cell biology - 1 Jun 2011
Mittal Rama Devi, Gangwar Ruchika, George Ginu P, Mittal Tulika, Kapoor Rakesh
Abstract excerpt
MicroRNAs (miRNA) are a class of small noncoding RNA molecules that have been implicated in a wide variety of cellular functions through post-transcriptional regulations on target genes. Common genetic variants (single-nucleotide polymorphisms, SNPs) in pre-miRNA genes may alter their expression and/or maturation effecting thousands of target mRNAs, resulting in varied functional consequences. Three common SNPs...
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