Article
Impact of polymorphisms in microRNA biogenesis genes on colon cancer risk and microRNA expression levels: a population-based, case-control study.
BMC medical genomics - 23 Apr 2016
Mullany Lila E, Herrick Jennifer S, Wolff Roger K, Buas Matthew F, Slattery Martha L
Abstract excerpt
BACKGROUND: MicroRNAs (miRNAs) have been implicated in the incidence and progression of cancer. It has been proposed that single nucleotide polymorphisms (SNPs) influence cancer risk due to their position within genes involved in miRNA synthesis and regulation. METHODS: Genes directly and indirectly involved in miRNA biogenesis were identified from the literature. We then identified SNPs within these regions....
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