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Article

Transcriptional regulation of human RANK ligand gene expression by E2F1.

Biochemical and biophysical research communications - 6 Jun 2008

Hu Yan, Sun Meng, Nadiminty Nagalakshmi, Lou Wei, Pinder Elaine, Gao Allen C

Abstract excerpt

Receptor activator of nuclear factor kappa B ligand (RANKL) is a critical osteoclastogenic factor involved in the regulation of bone resorption, immune function, the development of mammary gland and cardiovascular system. To understand the transcriptional regulation of RANKL, we amplified and characterized a 1890bp 5'-flanking sequence of human RANKL gene (-1782bp to +108bp relative to the transcription start...

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Identifiers

PMID: 18381203
DOI: 10.1016/j.bbrc.2008.03.106
PMCID: PMC2950805

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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