Article
Receptor activator of NF-kappaB ligand induction via Jak2 and Stat5a in mammary epithelial cells.
The Journal of biological chemistry - 14 Nov 2003
Srivastava Sunil, Matsuda Manabu, Hou Zhaoyuan, Bailey Jason P, Kitazawa Riko, Herbst Matthew P, Horseman Nelson D
Abstract excerpt
Prolactin (PRL) is the primary hormone that, in conjunction with local factors, leads to lobuloalveolar development during pregnancy. Recently, receptor activator of NF-kappaB ligand (RANKL) has been identified as one of the effector molecules essential for lobuloalveolar development. The molecular mechanisms by which PRL may induce RANKL expression have not been carefully examined. Here we report that RANKL...
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