Article
Interferon-gamma Low producer genotype +874 overrepresented in Bacillus Calmette-Guerin nonresponding children.
The Pediatric infectious disease journal - 1 Apr 2008
Anuradha Bandaru, Rakh Shilpa S, Ishaq Mohd, Murthy K J R, Valluri Vijaya Lakshmi
Abstract excerpt
BACKGROUND: There are limited reports on the influence of the immune regulatory genotypes on the efficacy of Bacillus Calmette-Guerin (BCG) in man. This study was designed to evaluate the influence of the cytokine genotype interferon (IFN)-gamma +874T/A on T cell in vitro assays in BCG nonresponders (negative to either in vivo or in vitro test with purified protein derivative or both). METHODS: Ninety healthy...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
