Interferon-gamma release assay performance in northeastern Brazil: influence of the IFNG+874 A>T polymorphism.

doi:10.1016/j.bjid.2018.04.004

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Article

Interferon-gamma release assay performance in northeastern Brazil: influence of the IFNG+874 A>T polymorphism.

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Jan 2000

Carneiro Valdirene Leão, Bendicho Maria Teresita, Santos Rosalina Guedes, Casela Marilda, Netto Eduardo M, Mota Scarlet Torres Moraes, Pina Iza Cristina Araújo, Nascimento Roberto Meyer, Freire Songeli Menezes, Barbosa Theolis

Abstract excerpt

INTRODUCTION: Latent tuberculosis infection diagnosis based on the release of interferon-gamma in cultures of peripheral blood cells stimulated with Mycobacterium tuberculosis antigens has replaced the tuberculin skin test in many countries with low tuberculosis prevalence. The IFN-γ production can be influenced by genetic polymorphisms, of which the IFNG+874 (rs62559044) locus is the most studied. We...

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PMID: 29787713
DOI: 10.1016/j.bjid.2018.04.004
PMCID: PMC9425666

Genes

IFNG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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