Article
Influence of single nucleotide polymorphisms of cytokine genes on anti-HBs antibody production after hepatitis B vaccination in a Japanese young adult population.
The journal of medical investigation : JMI - 1 Jan 2016
Yukimasa Nobuyasu, Sato Shoichi, Oboshi Wataru, Watanabe Toru, Uzawa Ryuichi
Abstract excerpt
Hepatitis B (HB) vaccination is one of the most efficient tools to prevent the transmission of the virus. Considerable variability exists in HB vaccine responses, with 5-10% of healthy Japanese adults demonstrating no response following a standard vaccination. Recently, polymorphisms of immune-regulatory genes, such as cytokine genes, have been reported to influence the immune response to HB vaccine. The aim of...
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