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Article

Establishment of a young mouse model and identification of an allelic variation of zmpB in complicated pneumonia caused by Streptococcus pneumoniae.

Critical care medicine - 1 Apr 2008

Hsieh Yu-Chia, Tsao Po-Nien, Chen Chi-Long, Lin Tzu-Lung, Lee Wen-Sen, Shao Pei-Lan, Lee Chin-Yun, Hsueh Po-Ren, Huang Li-Min, Wang Jin-Town

Abstract excerpt

OBJECTIVE: Complicated pneumonia, including necrotizing pneumonia, lung abscess, and empyema, caused by Streptococcus pneumoniae in children has been increasing. We thus determined to investigate its virulence in an animal model and to identify virulence factors of S. pneumoniae. DESIGN: Prospective, randomized, controlled animal study. SETTING: University medical laboratory. SUBJECTS: Male Balb/c-strain mice, 3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18379252
DOI: 10.1097/CCM.0b013e318169f0c3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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