Article

Cellular and molecular dynamics in the lungs of neonatal and juvenile mice in response to <i>E. coli</i>

2022-09-21

Abstract excerpt

Bacterial pneumonias cause significantly higher morbidity and mortality in neonates compared to other age groups. To understand the immune mechanisms that underlie these age-related differences, we employed a mouse model of E. coli pneumonia to examine cellular and molecular dynamics in immune responsiveness in neonates (PND 3-5) and juveniles (PND 12-18) at 24, 48, and 72 hours. Cytokine gene expression from who...

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Literature Corpus work: 7b1507b9-55a9-5f3b-8a35-af535853ef71
DOI: 10.1101/2022.09.21.508849

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