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Article

Association of an EAAT2 polymorphism with higher glutamate concentration in relapsing multiple sclerosis.

Journal of neuroimmunology - 1 Mar 2008

Pampliega Olatz, Domercq María, Villoslada Pablo, Sepulcre Jorge, Rodríguez-Antigüedad Alfredo, Matute Carlos

Abstract excerpt

Glutamate excitotoxicity contributes to oligodendrocyte and tissue damage in multiple sclerosis (MS). Here, we have examined if glutamate homeostasis is altered in plasma from MS patients. We initially observed that plasma glutamate levels are elevated in MS patients as compared to control subjects. In addition, we have studied the presence of a polymorphism sited in the promoter of the glutamate transporter...

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Share to Cell Line, Transformed
Share to Excitatory Amino Acid Transporter 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18378006
DOI: 10.1016/j.jneuroim.2008.01.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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