Article
Polymorphisms in the glial glutamate transporter SLC1A2 are associated with essential tremor.
Neurology - 17 Jul 2012
Thier Sandra, Lorenz Delia, Nothnagel Michael, Poremba Caroline, Papengut Frank, Appenzeller Silke, Paschen Steffen, Hofschulte Frank, Hussl Anna-Christina, Hering Sascha, Poewe Werner, Asmus Friedrich, Gasser Thomas, Schöls Ludger, Christensen Kaare, Nebel Almut, Schreiber Stefan, Klebe Stephan, Deuschl Günther, Kuhlenbäumer Gregor
Abstract excerpt
OBJECTIVE: Sporadic, genetically complex essential tremor (ET) is one of the most common movement disorders and may lead to severe impairment of the quality of life. Despite high heritability, the genetic determinants of ET are largely unknown. We performed the second genome-wide association study (GWAS) for ET to elucidate genetic risk factors of ET. METHODS: Using the Affymetrix Genome-Wide SNP Array 6.0...
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