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Article

Variants of the EAAT2 Glutamate Transporter Gene Promoter Are Associated with Cerebral Palsy in Preterm Infants.

Molecular neurobiology - 1 Mar 2018

Rajatileka Shavanthi, Odd David, Robinson Matthew T, Spittle Alexandra C, Dwomoh Louis, Williams Maggie, Harding David, Wagstaff Miles, Owen Marie, Crosby Charlene, Ching Jared, Molnár Elek, Luyt Karen, Váradi Anikó

Abstract excerpt

Preterm delivery is associated with neurodevelopmental impairment caused by environmental and genetic factors. Dysfunction of the excitatory amino acid transporter 2 (EAAT2) and the resultant impaired glutamate uptake can lead to neurological disorders. In this study, we investigated the role of single nucleotide polymorphisms (SNPs; g.-200C>A and g.-181A>C) in the EAAT2 promoter in susceptibility to brain injury...

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Identifiers

PMID: 28271401
DOI: 10.1007/s12035-017-0462-1
PMCID: PMC5840247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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