Article
Genetic heterogeneity in a susceptible region for essential hypertension among demographically different local populations in Japan.
Community genetics - 1 Jan 2008
Kumada Maki, Lkhagvasuren Munkhtulga, Utsumi Nanami, Omi Toshinori, Gotoh Takaya, Kamesaki Toyomi, Okuda Hiroshi, Kajii Eiji, Iwamoto Sadahiko
Abstract excerpt
OBJECTIVE: The aim of the study was to investigate genetic heterogeneity among local Japanese populations. METHODS: We performed a single nucleotide polymorphism (SNP) study of four demographically distinct local populations (population 1: a large city; population 2: isolated islands; populations 3 and 4: rural areas). Seventy SNPs in a region spanning 5 Mb of chromosome 17 known to be a candidate region for...
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