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Genetic differences in the two main groups of the Japanese population based on autosomal SNPs and haplotypes.

Journal of human genetics - 1 May 2012

Yamaguchi-Kabata Yumi, Tsunoda Tatsuhiko, Kumasaka Natsuhiko, Takahashi Atsushi, Hosono Naoya, Kubo Michiaki, Nakamura Yusuke, Kamatani Naoyuki

Abstract excerpt

Although the Japanese population has a rather low genetic diversity, we recently confirmed the presence of two main clusters (the Hondo and Ryukyu clusters) through principal component analysis of genome-wide single-nucleotide polymorphism (SNP) genotypes. Understanding the genetic differences between the two main clusters requires further genome-wide analyses based on a dense SNP set and comparison of haplotype...

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PMID: 22456480
DOI: 10.1038/jhg.2012.26

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