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Article

PprA: a novel protein from Deinococcus radiodurans that stimulates DNA ligation.

Molecular microbiology - 1 Oct 2004

Narumi Issay, Satoh Katsuya, Cui Suzhen, Funayama Tomoo, Kitayama Shigeru, Watanabe Hiroshi

Abstract excerpt

The extraordinary radiation resistance of Deinococcus radiodurans results from the efficient capacity of the bacterium to repair DNA double-strand breaks. By analysing the DNA damage repair-deficient mutant, KH311, a unique radiation-inducible gene (designated pprA) responsible for loss of radiation resistance was identified. Investigations in vitro showed that the gene product of pprA (PprA) preferentially bound...

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Source

Identifiers

PMID: 15458422
DOI: 10.1111/j.1365-2958.2004.04272.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

PprA: a novel protein from Deinococcus radiodurans that stimulates DNA ligation.PMID 15458422Read ↗

ATP-type DNA ligase requires other proteins for its activity in vitro and its operon components for radiation resistance in Deinococcus radiodurans in vivo.Semantic proximity Read ↗

Radiation response mechanisms of the extremely radioresistant bacterium Deinococcus radiodurans.Semantic proximity Read ↗

The PprA protein is required for accurate cell division of γ-irradiated Deinococcus radiodurans bacteria.Semantic proximity Read ↗

Characterization of the role of DR0171 in transcriptional response to radiation in the extremely radioresistant bacterium Deinococcus radiodurans.Semantic proximity Read ↗

Analysis of Deinococcus radiodurans's transcriptional response to ionizing radiation and desiccation reveals novel proteins that contribute to extreme radioresistance.Semantic proximity Read ↗

DNA Gyrase of Deinococcus radiodurans is characterized as Type II bacterial topoisomerase and its activity is differentially regulated by PprA in vitro.Semantic proximity Read ↗

PprI: a general switch responsible for extreme radioresistance of Deinococcus radiodurans.Semantic proximity Read ↗

The Deinococcus radiodurans DR1245 protein, a DdrB partner homologous to YbjN proteins and reminiscent of type III secretion system chaperones.Semantic proximity Read ↗

Structure-function study of deinococcal serine/threonine protein kinase implicates its kinase activity and DNA repair protein phosphorylation roles in radioresistance of Deinococcus radiodurans.Semantic proximity Read ↗

The Deinococcus radiodurans uvr A gene: identification of mutation sites in two mitomycin-sensitive strains and the first discovery of insertion sequence element from deinobacteria.Semantic proximity Read ↗

An RNA ligase from Deinococcus radiodurans.Semantic proximity Read ↗

The deinococcal DdrB protein is involved in an early step of DNA double strand break repair and in plasmid transformation through its single-strand annealing activity.Semantic proximity Read ↗

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