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Article

The genetic polymorphism of drug transporters: functional analysis approaches.

Pharmacogenomics - 1 Jan 2004

Ishikawa Toshihisa, Tsuji Akira, Inui Kenichi, Sai Yoshimichi, Anzai Naohiko, Wada Morimasa, Endou Hitoshi, Sumino Yasuhiro

Abstract excerpt

Evidence is accumulating to strongly suggest that drug transporters are one of the determining factors governing the pharmacokinetic profile of drugs. To date, a variety of drug transporters have been cloned and classified as solute carriers and ATP-binding cassette transporters. Such drug transporters are expressed in various tissues such as the intestine, brain, liver, and kidney, and play critical roles in the...

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Identifiers

PMID: 14683421
DOI: 10.1517/phgs.5.1.67.25683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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