Article
A dualistic model for endometrial carcinogenesis based on immunohistochemical and molecular genetic analyses.
Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 1997
Lax S F, Kurman R J
Abstract excerpt
Clinicopathological, immunohistochemical and molecular genetic analyses of endometrial carcinoma suggest different pathogenetic pathways for endometrioid and serous carcinoma. Most endometrioid carcinomas are associated with endometrial hyperplasia, are ER/PR positive, p53 negative and express lo...
Topics
- Biomarkers, Tumor
- Carcinoma
- Carcinoma, Endometrioid
- Cystadenocarcinoma, Serous
- Endometrial Neoplasms
- Female
- Genes, ras
- Humans
- Immunohistochemistry
- Ki-67 Antigen
- Mutation
- Ovarian Neoplasms
- Receptors, Estrogen
- Receptors, Progesterone
- Tumor Suppressor Protein p53
