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Article

A dualistic model for endometrial carcinogenesis based on immunohistochemical and molecular genetic analyses.

Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 1997

Lax S F, Kurman R J

Abstract excerpt

Clinicopathological, immunohistochemical and molecular genetic analyses of endometrial carcinoma suggest different pathogenetic pathways for endometrioid and serous carcinoma. Most endometrioid carcinomas are associated with endometrial hyperplasia, are ER/PR positive, p53 negative and express low Ki-67. In contrast, almost all serous carcinomas develop from endometrial intraepithelial carcinoma (EIC) in a...

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PMID: 9474874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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