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Article

14-3-3 proteins block apoptosis and differentially regulate MAPK cascades.

The EMBO journal - 1 Feb 2000

Xing H, Zhang S, Weinheimer C, Kovacs A, Muslin A J

Abstract excerpt

14-3-3 family members are dimeric phosphoserine-binding proteins that participate in signal transduction and checkpoint control pathways. In this work, dominant-negative mutant forms of 14-3-3 were used to disrupt 14-3-3 function in cultured cells and in transgenic animals. Transfection of cultur...

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Identifiers

PMID: 10654934
DOI: 10.1093/emboj/19.3.349
PMCID: PMC305572

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10654934-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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