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Article

Surface loop dynamics in adeno-associated virus capsid assembly.

Journal of virology - 1 Jun 2008

DiPrimio Nina, Asokan Aravind, Govindasamy Lakshmanan, Agbandje-McKenna Mavis, Samulski R Jude

Abstract excerpt

The HI loop is a prominent domain on the adeno-associated virus (AAV) capsid surface that extends from each viral protein (VP) subunit overlapping the neighboring fivefold VP. Despite the highly conserved nature of the residues at the fivefold pore, the HI loops surrounding this critical region vary significantly in amino acid sequence between the AAV serotypes. In order to understand the role of this unique...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18367523
DOI: 10.1128/JVI.02721-07
PMCID: PMC2395211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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