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The structure of the Human Adenovirus 7 virus-like particles reveals that pentons and core-genome promote hexon-pIIIa interactions during capsid maturation

2025-09-22

Abstract excerpt

Members of the Adenoviridae family routinely infect humans, exhibit significant genetic diversity, and are associated with a variety of illnesses. Types 4 and 7 frequently circulate in the United States and are major causes of respiratory disease. Infections can result in hospitalization and, in severe cases, death. Although a live wild-type-virus vaccine targeting these two types exists, its use is restricted to...

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Literature Corpus work
7d4be183-9fc3-59c8-8199-5442c6efbd10
DOI
10.1101/2025.09.22.677823
Open publication

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The structure of the Human Adenovirus 7 virus-like particles reveals that pentons and core-genome promote hexon-pIIIa interactions during capsid maturationDOI 10.1101/2025.09.22.677823
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