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Article

Establishment of a new method for precisely determining the functions of individual mitochondrial genes, using Dictyostelium cells.

BMC genetics - 21 Mar 2008

Chida Junji, Amagai Aiko, Tanaka Masashi, Maeda Yasuo

Abstract excerpt

BACKGROUND: Disruption of mitochondrial genes may become a powerful tool for elucidating precisely the functions of individual mitochondrial genes. However, it is generally difficult to manipulate genetically mitochondrial genes, because 1) a mitochondrion is surrounded by inner and outer membranes, and 2) there are a large number of mtDNA copies in a single cell. This is the reason why we tried to establish a...

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Identifiers

PMID: 18366713
DOI: 10.1186/1471-2156-9-25
PMCID: PMC2330148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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