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Article

The Inflamma-type: a patient phenotype characterized by a dysregulated inflammatory response after lower extremity articular fracture.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Jan 2023

Jacobs Cale A, Olsen Zachary M, Marchand Lucas S, Kraus Virginia B, Anderson Donald D, Haller Justin

Abstract excerpt

Synovial fluid was collected from 113 patients who had suffered tibial plateau (n = 48), tibial plafond (n = 29), or rotational ankle fractures (n = 36). Concentrations of IL-1β, IL-1RA, IL-6, IL-8, IL-10, and MMP-1, -3, and -13 were quantified using multiplex assays. A cluster analysis of synovial fluid biomarker concentrations was performed. Patient demographics, fracture type, Injury Severity Score (ISS),...

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PMID: 36309627
DOI: 10.1007/s00011-022-01661-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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